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Due to slight changes in surface chemistry, the implant surface is transferred from a hydrophobic state to a superhydrophilic surface condition (INICELL®).
These properties of INICELL® promote spontaneous and complete wetting of the implant with physiological fluids, especially blood (Tugulu 2010).
This accelerates the wound healing cascade (Milleret 2011, Burkhardt 2016, Burkhardt 2017), which is reflected in higher bone to implant contact and higher implant stability in the early healing phase. From a clinical point of view, this results in a low early failure rate (0.5%, Le Gac 2015) and a safe and predictable treatment option after three weeks (Hicklin 2015, Hinkle 2014). A shortened healing time can also be achieved in patients with reduced bone quality (Grades 3 and 4) (Held 2014).
The APLIQUIQ® container contains the conditioning agent, implant and healing cap. For outstanding product development and design, Thommen Medical AG has been honored with the distinguished reddot design product award 2011. APLIQUIQ® was selected by the reddot committee based on the product’s practical design, useful functionality and innovative technology.
Many consider the sandblasted, thermal acid-etched microrough surface to be the gold standard for implant surface modification.
The advantage for implants that feature a microrough surface is that they establish excellent functional and structural connections between the bone and the implant surface, leading to higher intrinsic implant stability (Buser 1999).
Specifically, the microrough surface enhances the interlocking of the implant surface with bone and has been shown to promote the differentiation of osteogenic cells in-vitro (Boyan 2001).
Scanning electron microscopic images of the microrough sandblasted and thermal acid-etched surface of Thommen implants with increasing magnification.
Fluorescence microscopic picture of the protein film on model substrates five minutes after primary contact with protein solution.
The quantity, composition, homogenity and functionality of the protein film deposited on the implant surface directly influences the healing and osseointegration processes to follow.
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